Hatem FESSI

Professeur

  • Génie Pharmacotechnique

Nanosphères et Nanocapsules


Bureau 1 Laboratoire d’Automatique et de Génie des Procédés (LAGEP), Université Claude Bernard Lyon 1, bât 308G – ESCPE-Lyon, 2ème étage – 43 bd du 11 Novembre 1918 G219 Villeurbanne 69622 France

Fax bureau 1: 04 72 43 16 82Téléphone bureau 1: 04 72 43 18 64

Bio

Titres Universitaires:

1972 : Maître ès Sciences Chimie
1976 : Pharmacien, Faculté de Pharmacie de CHATENAY-MALABRY.
1977 : D.E.S.S. de Pharmacotechnie industrielle, PARIS XI.
1978 : D.E.A. de Biopharmacie et Recherche Galénique, PARIS XI.
1982 : Doctorat d’Etat ès Sciences Pharmaceutiques, PARIS XI.
1988 : Diplôme d’habilitation à diriger des recherches, PARIS XI.

Fonctions Administratives :
- Membre élu du conseil de l’ISPB-Faculté de Pharmacie de l’Université de LYON I
- Président de la commission des finances de l’I.S.P.B.- Faculté de Pharmacie de l’Université de LYON I.

Organismes scientifiques
- Expert galéniste au groupe de travail pharmaceutique de l’ANSM pour l’autorisation de mise sur le marché des médicaments.
- Expert galéniste au groupe de travail Génériques de l’ANSM pour l’autorisation de mise sur le marché des médicaments.
- Expert galéniste au groupe de travail pédiatrique de l’EMA

Depuis 2003 : Directeur du Laboratoire d’Automatique et de Génie des Procédés (LAGEP) – UMR CNRS 5007

Résultats scientifiques
Les recherches actuelles, dont la thématique est la vectorisation des médicaments, se sont développées selon quatre axes complémentaires:
-Mise au point de procédés originaux d’obtention de systèmes colloïdaux manométriques biocompatibles et biodégradables (Nanosphères et Nanocapsules polymériques, Nanosphères protéiques, Liposomes, Emulsions sub-microniques injectables, Systèmes colloïdaux à base de cyclodextrines modifiées)
-Valorisation biologique et pharmaceutique des systèmes colloïdaux obtenus en termes d’interaction avec les muqueuses. Application à l’amélioration de la biodisponibilité et de la tolérance locale des médicaments administrés par différentes voies (orale, intramusculaire, oculaire)
-Etude des potentialités thérapeutiques de ces systèmes : Application à l’étude des interactions entre macrophages et colloïdes dans le traitement et la prévention des métastases (immunomodulateurs), des parasitoses (leischmanicides) et des infections (antifongiques).
-Génie Pharmacotechnique: étude de la transposition industrielle des procédés de préparation des systèmes colloïdaux.

Production scientifique

Brevets : 56
Publications : 264 h index :40 h index (W.O.S) : 42
Chapitres d’ouvrages :10
Communications : 205
Direction et co-direction de thèses d’Université : 45

Poly(hydroxybutyrate-co-hydroxyvalerate) microspheres for the encapsulation and controlled release of heparin

date:2016
références bibliographiques:

Monnier, Alexandre, Nida SHEIBAT -OTHMAN, J.M. Chenal, A. Martins Dos Santos, and H. Fessi. “Poly(hydroxybutyrate-Co-Hydroxyvalerate) Microspheres for the Encapsulation and Controlled Release of Heparin.” 5, no. 1 (2016).

Journal of Colloid Science and Biotechnology

 

Advances in psoriasis physiopathology and treatments: Up to date of mechanistic insights and perspectives of novel therapies based on innovative skin drug delivery systems (ISDDS)

date:2016
références bibliographiques:

Sala, M., A. Elaissari, and H. Fessi. “Advances in Psoriasis Physiopathology and Treatments: Up to Date of Mechanistic Insights and Perspectives of Novel Therapies Based on Innovative Skin Drug Delivery Systems (ISDDS).” 239 (October 2016): 182–202. doi:10.1016/j.jconrel.2016.07.003.
Pages:182-202

Journal of Controlled Release

 

Carbon nanotubes from synthesis to in vivo biomedical applications

date:2016
références bibliographiques:

Sajid, Muhammad Imran, Usama Jamshaid, Talha Jamshaid, Nadiah Zafar, H. Fessi, and Abdelhamid Elaissari. “Carbon Nanotubes from Synthesis to in Vivo Biomedical Applications.” 501, no. 1–2 (March 2016): 278–99. doi:10.1016/j.ijpharm.2016.01.064.
Pages:278-299

International Journal of Pharmaceutics

 

Preparation and characterization of biodegradable polyhydroxybutyrate-co-hydroxyvalerate/polyethylene glycol-based microspheres

date:2016
références bibliographiques:

Monnier, Alexandre, Charlotte Rombouts, Dania Kouider, Imad About, Hatem Fessi, and Nida SHEIBAT -OTHMAN. “Preparation and Characterization of Biodegradable Polyhydroxybutyrate-Co-Hydroxyvalerate/polyethylene Glycol-Based Microspheres.” 513, no. 1–2 (2016): 49–61. doi:10.1016/j.ijpharm.2016.08.066.
Pages:49-61

International Journal of Pharmaceutics

 

Aminodextran polymer-functionalized reactive magnetic emulsions for potential theranostic applications

date:2016
références bibliographiques:

Lima-Tenório, Michele K., Edgardo A.Gómez Pineda, Nasir M. Ahmad, Geraldine Agusti, Sadia Manzoor, Dounia Kabbaj, Hatem Fessi, and Abdelhamid Elaissari. “Aminodextran Polymer-Functionalized Reactive Magnetic Emulsions for Potential Theranostic Applications.” 145 (September 2016): 373–81. doi:10.1016/j.colsurfb.2016.05.020.
Pages:373-381

Colloids and Surfaces B: Biointerfaces

 

Submicron magnetic core conducting polypyrrole polymer shell: Preparation and characterization

date:2016
références bibliographiques:

Tenório-Neto, Ernandes Taveira, Abdoullatif Baraket, Dounia Kabbaj, Nadia Zine, Abdelhamid Errachid, Hatem Fessi, Marcos Hiroiuqui Kunita, and Abdelhamid Elaissari. “Submicron Magnetic Core Conducting Polypyrrole Polymer Shell: Preparation and Characterization.” 61 (April 2016): 688–94. doi:10.1016/j.msec.2015.12.052.
Pages:688-694

Materials Science and Engineering: C

 

Preparation of gold nanoparticles and determination of their particles size via different methods

date:2016
références bibliographiques:

Iqbal, Muhammad, Gisele Usanase, Kafia Oulmi, Fairouz Aberkane, Tahar Bendaikha, Hatem Fessi, Nadia Zine, Géraldine Agusti, El-Salhi Errachid, and Abdelhamid Elaissari. “Preparation of Gold Nanoparticles and Determination of Their Particles Size via Different Methods.” 79 (July 2016): 97–104. doi:10.1016/j.materresbull.2015.12.026.
Pages:97-104

Materials Research Bulletin

 

Biodegradable microparticles preparation by double emulsification—Solvent extraction method: A Systematic study

date:2016
références bibliographiques:

Baena-Aristizábal, Claudia M., Hatem Fessi, Abdelhamid Elaissari, and Claudia E. Mora-Huertas. “Biodegradable Microparticles Preparation by Double emulsification—Solvent Extraction Method: A Systematic Study.” 492 (March 2016): 213–29. doi:10.1016/j.colsurfa.2015.11.067.
Pages:213-229

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Clove essential oil-in-cyclodextrin-in-liposomes in the aqueous and lyophilized states: From laboratory to large scale using a membrane contactor

date:2016
références bibliographiques:

Sebaaly, Carine, Catherine Charcosset, Serge Stainmesse, Hatem Fessi, and Hélène Greige-Gerges. “Clove Essential Oil-in-Cyclodextrin-in-Liposomes in the Aqueous and Lyophilized States: From Laboratory to Large Scale Using a Membrane Contactor.” 138 (March 2016): 75–85. doi:10.1016/j.carbpol.2015.11.053.
Pages:75-85

Carbohydrate Polymers

 

Formulation of orodispersible films for paediatric therapy: investigation of feasibility and stability for tetrabenazine as drug model

date:2016
références bibliographiques:

Senta-Loys, Zoé, Sandrine Bourgeois, Cyril Pailler-Mattei, Géraldine Agusti, Stéphanie Briançon, and Hatem Fessi. “Formulation of Orodispersible Films for Paediatric Therapy: Investigation of Feasibility and Stability for Tetrabenazine as Drug Model.” , September 2016. doi:10.1111/jphp.12627.

Journal of Pharmacy and Pharmacology

 

Plant extracts: from encapsulation to application

date:2016
références bibliographiques:

Armendáriz-Barragán, Brenda, Nadiah Zafar, Waisudin Badri, Sergio Arturo Galindo-Rodríguez, Dounia Kabbaj, Hatem Fessi, and Abdelhamid Elaissari. “Plant Extracts: From Encapsulation to Application.” 13, no. 8 (2016): 1165–75. doi:10.1080/17425247.2016.1182487.
Pages:1165-1175

Expert Opinion on Drug Delivery

 

Antimicrobial films containing microparticles for the enhancement of long-term sustained release

date:2016
références bibliographiques:

Bile, Jessica, Marie-Alexandrine Bolzinger, Jean-Pierre Valour, Hatem Fessi, and Yves Chevalier. “Antimicrobial Films Containing Microparticles for the Enhancement of Long-Term Sustained Release.” 42, no. 5 (2016): 818–24. doi:10.3109/03639045.2015.1081237.
Pages:818-824

Drug Development and Industrial Pharmacy

 

Microencapsulation of rifampicin for the prevention of endophthalmitis: In vitro release studies and antibacterial assessment

date:2016
références bibliographiques:

Lee, Mi Yeon, Sandrine Bourgeois, Eyad Almouazen, Jocelyne Pelletier, François Renaud, Hatem Fessi, and Laurent Kodjikian. “Microencapsulation of Rifampicin for the Prevention of Endophthalmitis: In Vitro Release Studies and Antibacterial Assessment.” , March 2016. doi:10.1016/j.ijpharm.2016.03.026.

International Journal of Pharmaceutics

 

Freeze-drying of emulsified systems: A review

date:2016
références bibliographiques:

Morais, Andreza Rochelle do Vale, Éverton do Nascimento Alencar, Francisco Humberto Xavier Júnior, Christian Melo de Oliveira, Henrique Rodrigues Marcelino, Gillian Barratt, Hatem Fessi, Eryvaldo Sócrates Tabosa do Egito, and Abdelhamid Elaissari. “Freeze-Drying of Emulsified Systems: A Review.” 503, no. 1–2 (April 2016): 102–14. doi:10.1016/j.ijpharm.2016.02.047.
Pages:102-114

International Journal of Pharmaceutics

 

Elaboration of ammonio methacrylate copolymer based spongy cationic particles via double emulsion solvent evaporation process

date:2016
références bibliographiques:

Zafar, Nadiah, Ahmad Bitar, Jean Pierre Valour, Hatem Fessi, and Abdelhamid Elaissari. “Elaboration of Ammonio Methacrylate Copolymer Based Spongy Cationic Particles via Double Emulsion Solvent Evaporation Process.” 61 (April 2016): 85–96. doi:10.1016/j.msec.2015.12.017.
Pages:85-96

Materials Science and Engineering: C

 

Preparation of chitosan–TPP nanoparticles using microengineered membranes – Effect of parameters and encapsulation of tacrine

date:2015
références bibliographiques:

Hassani, S., A. Laouini, H. Fessi, and C. Charcosset. “Preparation of chitosan–TPP Nanoparticles Using Microengineered Membranes – Effect of Parameters and Encapsulation of Tacrine.” 482 (October 2015): 34–43. doi:10.1016/j.colsurfa.2015.04.006.
Pages:34-43

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Encapsulation of alendronate sodium by nanoprecipitation and double emulsion: From preparation to in vitro studies

date:2015
références bibliographiques:

Miladi, K., S. Sfar, H. Fessi, and A. Elaissari. “Encapsulation of Alendronate Sodium by Nanoprecipitation and Double Emulsion: From Preparation to in Vitro Studies.” 72 (October 2015): 24–33. doi:10.1016/j.indcrop.2015.01.079.
Pages:24-33

Industrial Crops and Products

 

Enhancement of alendronate encapsulation in chitosan nanoparticles

date:2015
références bibliographiques:

Miladi, K., S. Sfar, H. Fessi, and A. Elaissari. “Enhancement of Alendronate Encapsulation in Chitosan Nanoparticles.” 30 (December 2015): 391–96. doi:10.1016/j.jddst.2015.04.007.
Pages:391-396

Journal of Drug Delivery Science and Technology

 

The parameters influencing the morphology of poly(É›-caprolactone) microspheres and the resulting release of encapsulated drugs

date:2015
références bibliographiques:

Bile, Jessica, Marie-Alexandrine Bolzinger, Charlène Vigne, Olivier Boyron, Jean-Pierre Valour, Hatem Fessi, and Yves Chevalier. “The Parameters Influencing the Morphology of Poly(É›-Caprolactone) Microspheres and the Resulting Release of Encapsulated Drugs.” 494, no. 1 (October 2015): 152–66. doi:10.1016/j.ijpharm.2015.07.068.
Pages:152-166

International Journal of Pharmaceutics

 

TGA and magnetization measurements for determination of composition and polymer conversion of magnetic hybrid particles: MAGNETIC HYBRID PARTICLES

date:2015
références bibliographiques:

Tenório-Neto, Ernandes Taveira, Talha Jamshaid, Mohamed Eissa, Marcos Hiroiuqui Kunita, Nadia Zine, Géraldine Agusti, Hatem Fessi, Abdelhamid Errachid El-Salhi, and Abdelhamid Elaissari. “TGA and Magnetization Measurements for Determination of Composition and Polymer Conversion of Magnetic Hybrid Particles: MAGNETIC HYBRID PARTICLES.” 26, no. 10 (October 2015): 1199–1208. doi:10.1002/pat.3562.
Pages:1199-1208

Polymers for Advanced Technologies

 

Preparation of liposomes at large scale using the ethanol injection method: Effect of scale-up and injection devices

date:2015
références bibliographiques:

Charcosset, Catherine, Audrey Juban, Jean-Pierre Valour, Sébastien Urbaniak, and Hatem Fessi. “Preparation of Liposomes at Large Scale Using the Ethanol Injection Method: Effect of Scale-up and Injection Devices.” 94 (2015): 508–15. doi:10.1016/j.cherd.2014.09.008.
Pages:508-515

Chemical Engineering Research and Design

 

Preparation of liposomes at large scale using the ethanol injection method: Effect of scale-up and injection devices

date:2015
références bibliographiques:

Charcosset, Catherine, Audrey Juban, Jean-Pierre Valour, Sébastien Urbaniak, and Hatem Fessi. “Preparation of Liposomes at Large Scale Using the Ethanol Injection Method: Effect of Scale-up and Injection Devices.” 94 (February 2015): 508–15. doi:10.1016/j.cherd.2014.09.008.
Pages:508-515

Chemical Engineering Research and Design

 

Submicron polycaprolactone particles as a carrier for imaging contrast agent for in vitro applications

date:2015
références bibliographiques:

Iqbal, Muhammad, Sophie Robin, Philippe Humbert, Céline Viennet, Geraldine Agusti, Hatem Fessi, and Abdelhamid Elaissari. “Submicron Polycaprolactone Particles as a Carrier for Imaging Contrast Agent for in Vitro Applications.” 136 (December 2015): 488–95. doi:10.1016/j.colsurfb.2015.09.045.
Pages:488-495

Colloids and Surfaces B: Biointerfaces

 

Elaboration of sponge-like particles for textile functionalization and skin penetration

date:2015
références bibliographiques:

Bitar, Ahmad, Nadiah Zafar, Jean Pierre Valour, Géraldine Agusti, Hatem Fessi, Philippe Humbert, Sophie Robin, Céline Viennet, Nathalie Lévêque, and Abdelhamid Elaissari. “Elaboration of Sponge-like Particles for Textile Functionalization and Skin Penetration.” 293, no. 10 (October 2015): 2967–77. doi:10.1007/s00396-015-3704-7.
Pages:2967-2977

Colloid and Polymer Science

 

Preparation and characterization of clove essential oil-loaded liposomes

date:2015
références bibliographiques:

Sebaaly, Carine, Alia Jraij, Hatem Fessi, Catherine Charcosset, and Hélène Greige-Gerges. “Preparation and Characterization of Clove Essential Oil-Loaded Liposomes.” 178 (July 2015): 52–62. doi:10.1016/j.foodchem.2015.01.067.
Pages:52-62

Food Chemistry

 

Double emulsion solvent evaporation techniques used for drug encapsulation

date:2015
références bibliographiques:

Iqbal, Muhammad, Nadiah Zafar, Hatem Fessi, and Abdelhamid Elaissari. “Double Emulsion Solvent Evaporation Techniques Used for Drug Encapsulation.” 496, no. 2 (December 2015): 173–90. doi:10.1016/j.ijpharm.2015.10.057.
Pages:173-190

International Journal of Pharmaceutics

 

Gene therapy and DNA delivery systems

date:2014
références bibliographiques:

Ibraheem, D., A. Elaissari, and H. Fessi. “Gene Therapy and DNA Delivery Systems.” 459, no. 1–2 (January 2014): 70–83. doi:10.1016/j.ijpharm.2013.11.041.
Pages:70-83

International Journal of Pharmaceutics

 

Preparation and Characterization of Amorphous Solid Dispersions of Nimesulide in Cyclodextrin Copolymers

date:2014
références bibliographiques:

Skiba, M., M. Lahiani-Skiba, N. Milon, F. Bounoure, and H. Fessi. “Preparation and Characterization of Amorphous Solid Dispersions of Nimesulide in Cyclodextrin Copolymers.” 14, no. 4 (April 1, 2014): 2772–79. doi:10.1166/jnn.2014.8587.
Pages:2772-2779

Journal of Nanoscience and Nanotechnology

 

Characterization of different vitamin E carriers intended for pulmonary drug delivery

date:2014
références bibliographiques:

Laouini, A., V. Andrieu, L. Vecellio, H. Fessi, and C. Charcosset. “Characterization of Different Vitamin E Carriers Intended for Pulmonary Drug Delivery.” 471, no. 1–2 (August 2014): 385–90. doi:10.1016/j.ijpharm.2014.05.062.
Pages:385-390

International Journal of Pharmaceutics

 

Effects of process parameters on the colloidal properties of polycaprolactone microparticles prepared by double emulsion like process

date:2014
références bibliographiques:

Ibraheem, D., M. Iqbal, G. Agusti, H. Fessi, and A. Elaissari. “Effects of Process Parameters on the Colloidal Properties of Polycaprolactone Microparticles Prepared by Double Emulsion like Process.” 445 (March 2014): 79–91. doi:10.1016/j.colsurfa.2014.01.012.
Pages:79-91

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Use of dynamic membranes for the preparation of vitamin E-loaded lipid particles: An alternative to prevent fouling observed in classical cross-flow emulsification

date:2014
références bibliographiques:

Laouini, A., C. Charcosset, H. Fessi, and K. Schroen. “Use of Dynamic Membranes for the Preparation of Vitamin E-Loaded Lipid Particles: An Alternative to Prevent Fouling Observed in Classical Cross-Flow Emulsification.” 236 (January 2014): 498–505. doi:10.1016/j.cej.2013.10.053.
Pages:498-505

Chemical Engineering Journal

 

Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions

date:2014
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Claire Bordes, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure Sensitive Adhesive by Spray-Cooling: Optimum Formulation and Processing Conditions.” 25, no. 1 (January 2014): 292–300. doi:10.1016/j.apt.2013.05.004.
Pages:292-300

Advanced Powder Technology

 

Production of liposomes using microengineered membrane and co-flow microfluidic device

date:2014
références bibliographiques:

Vladisavljević, Goran T., Abdallah Laouini, Catherine Charcosset, Hatem Fessi, Hemaka C.H. Bandulasena, and Richard G. Holdich. “Production of Liposomes Using Microengineered Membrane and Co-Flow Microfluidic Device.” 458 (September 2014): 168–77. doi:10.1016/j.colsurfa.2014.03.016.
Pages:168-177

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Morphological and physicochemical characterization of liposomes loading cucurbitacin E, an anti-proliferative natural tetracyclic triterpene

date:2014
références bibliographiques:

Habib, Lamice, Alia Jraij, Nathalie Khreich, Hatem Fessi, Catherine Charcosset, and Hélène Greige-Gerges. “Morphological and Physicochemical Characterization of Liposomes Loading Cucurbitacin E, an Anti-Proliferative Natural Tetracyclic Triterpene.” 177 (January 2014): 64–70. doi:10.1016/j.chemphyslip.2013.11.006.
Pages:64-70

Chemistry and Physics of Lipids

 

Towards a One-Step Synthesis and Encapsulation of Acentric Iron Iodate (Fe(IO<SUB>3</SUB>)<SUB>3</SUB>) Nanocrystals via Inverse Miniemulsion

date:2014
références bibliographiques:

Ladj, Rachid, Mohamed M. Eissa, Jean-Pierre Valour, Yannick Mugnier, Ronan Le Dantec, Hatem Fessi, Marc Dubled, Christine Galez, and Abdelhamid Elaissari. “Towards a One-Step Synthesis and Encapsulation of Acentric Iron Iodate (Fe(IO<SUB>3</SUB>)<SUB>3</SUB>) Nanocrystals via Inverse Miniemulsion.” 6, no. 1 (January 1, 2014): 102–10. doi:10.1166/sam.2014.1685.
Pages:102-110

Science of Advanced Materials

 

Cyclodextrin containing biodegradable particles: From preparation to drug delivery applications

date:2014
références bibliographiques:

Zafar, Nadiah, Hatem Fessi, and Abdelhamid Elaissari. “Cyclodextrin Containing Biodegradable Particles: From Preparation to Drug Delivery Applications.” 461, no. 1–2 (January 2014): 351–66. doi:10.1016/j.ijpharm.2013.12.004.
Pages:351-366

International Journal of Pharmaceutics

 

Optimisation of rosemary oil encapsulation in polycaprolactone and scale-up of the process

date:2014
références bibliographiques:

Ephrem, Elissa, Hélène Greige-Gerges, Hatem Fessi, and Catherine Charcosset. “Optimisation of Rosemary Oil Encapsulation in Polycaprolactone and Scale-up of the Process.” 31, no. 8 (December 2014): 746–53. doi:10.3109/02652048.2014.918669.
Pages:746-753

Journal of Microencapsulation

 

Structural elucidation of two photolytic degradation products of tetrabenazine

date:2014
références bibliographiques:

Bourezg, Zouaoui, Nathalie Cartiser, Laurent Ettouati, Jean Guillon, Aline Lacoudre, Noël Pinaud, Marc Le Borgne, and Hatem Fessi. “Structural Elucidation of Two Photolytic Degradation Products of Tetrabenazine.” 91 (March 2014): 138–43. doi:10.1016/j.jpba.2013.12.032.
Pages:138-143

Journal of Pharmaceutical and Biomedical Analysis

 

Preparation of liposomes: A novel application of microengineered membranes–From laboratory scale to large scale

date:2013
références bibliographiques:

Laouini, A., C. Charcosset, H. Fessi, R.G. Holdich, and G.T. Vladisavljević. “Preparation of Liposomes: A Novel Application of Microengineered membranes–From Laboratory Scale to Large Scale.” 112 (December 2013): 272–78. doi:10.1016/j.colsurfb.2013.07.066.
Pages:272-278

Colloids and Surfaces B: Biointerfaces

 

Drug carriers in osteoporosis: Preparation, drug encapsulation and applications

date:2013
références bibliographiques:

Miladi, K., S. Sfar, H. Fessi, and A. Elaissari. “Drug Carriers in Osteoporosis: Preparation, Drug Encapsulation and Applications.” 445, no. 1–2 (March 2013): 181–95. doi:10.1016/j.ijpharm.2013.01.031.
Pages:181-195

International Journal of Pharmaceutics

 

Preparation of liposomes: a novel application of microengineered membranes – investigation of the process parameters and application to the encapsulation of vitamin E

date:2013
références bibliographiques:

Laouini, A., C. Charcosset, H. Fessi, R.G. Holdich, and G.T. Vladisavljević. “Preparation of Liposomes: A Novel Application of Microengineered Membranes – Investigation of the Process Parameters and Application to the Encapsulation of Vitamin E.” 3, no. 15 (2013): 4985. doi:10.1039/c3ra23411h.
Pages:4985

RSC Advances

 

Individual inorganic nanoparticles: preparation, functionalization and in vitro biomedical diagnostic applications

date:2013
références bibliographiques:

Ladj, R., A. Bitar, M. Eissa, Y. Mugnier, R. Le Dantec, H. Fessi, and A. Elaissari. “Individual Inorganic Nanoparticles: Preparation, Functionalization and in Vitro Biomedical Diagnostic Applications.” 1, no. 10 (2013): 1381. doi:10.1039/c2tb00301e.
Pages:1381

Journal of Materials Chemistry B

 

Preparation of Bovine Serum Albumin (BSA) nanoparticles by desolvation using a membrane contactor: A new tool for large scale production

date:2013
références bibliographiques:

Yedomon, B., H. Fessi, and C. Charcosset. “Preparation of Bovine Serum Albumin (BSA) Nanoparticles by Desolvation Using a Membrane Contactor: A New Tool for Large Scale Production.” 85, no. 3 (November 2013): 398–405. doi:10.1016/j.ejpb.2013.06.014.
Pages:398-405

European Journal of Pharmaceutics and Biopharmaceutics

 

Iodinated nano-emulsions as contrast agents for preclinical X-ray imaging: Impact of the free surfactants on the pharmacokinetics

date:2013
références bibliographiques:

Hallouard, François, Stéphanie Briançon, Nicolas Anton, Xiang Li, Thierry Vandamme, and Hatem Fessi. “Iodinated Nano-Emulsions as Contrast Agents for Preclinical X-Ray Imaging: Impact of the Free Surfactants on the Pharmacokinetics.” 83, no. 1 (January 2013): 54–62. doi:10.1016/j.ejpb.2012.09.003.
Pages:54-62

European Journal of Pharmaceutics and Biopharmaceutics

 

A safe and practical method for the preparation of 7α-thioether and thioester derivatives of spironolactone

date:2013
références bibliographiques:

Agusti, Géraldine, Sandrine Bourgeois, Nathalie Cartiser, Hatem Fessi, Marc Le Borgne, and Thierry Lomberget. “A Safe and Practical Method for the Preparation of 7α-Thioether and Thioester Derivatives of Spironolactone.” 78, no. 1 (January 2013): 102–7. doi:10.1016/j.steroids.2012.09.005.
Pages:102-107

Steroids

 

pH-Sensitive Micelles for Targeted Drug Delivery Prepared Using a Novel Membrane Contactor Method

date:2013
références bibliographiques:

Laouini, Abdallah, Konstantinos P. Koutroumanis, Catherine Charcosset, Stella Georgiadou, Hatem Fessi, Richard G. Holdich, and Goran T. Vladisavljević. “pH-Sensitive Micelles for Targeted Drug Delivery Prepared Using a Novel Membrane Contactor Method.” 5, no. 18 (September 25, 2013): 8939–47. doi:10.1021/am4018237.
Pages:8939-8947

ACS Applied Materials & Interfaces

 

Essential oils encapsulated in liposomes: a review

date:2013
références bibliographiques:

Sherry, Mirna, Catherine Charcosset, Hatem Fessi, and Hélène Greige-Gerges. “Essential Oils Encapsulated in Liposomes: A Review.” 23, no. 4 (December 2013): 268–75. doi:10.3109/08982104.2013.819888.
Pages:268-275

Journal of Liposome Research

 

New oil-in-water magnetic emulsion as contrast agent for in vivo magnetic resonance imaging (MRI)

date:2013
références bibliographiques:

Ahmed, Naveed, Chiraz Jaafar-Maalej, Mohamed Mahmoud Eissa, Hatem Fessi, and Abdelhamid Elaissari. “New Oil-in-Water Magnetic Emulsion as Contrast Agent for in Vivo Magnetic Resonance Imaging (MRI).” 9, no. 9 (January 1, 2013): 1579–85. doi:10.1166/jbn.2013.1644.
Pages:1579-1585

Journal of Biomedical Nanotechnology

 

Usefulness of Controlled Release of Growth Factors in Investigating the Early Events of Dentin-pulp Regeneration

date:2013
références bibliographiques:

Mathieu, Sylvie, Charlotte Jeanneau, Nida SHEIBAT -OTHMAN, Nader Kalaji, Hatem FESSI, and Imad About. “Usefulness of Controlled Release of Growth Factors in Investigating the Early Events of Dentin-Pulp Regeneration.” 39, no. 2 (2013): 228–35. doi:10.1016/j.joen.2012.11.007.
Pages:228-235

Journal of Endodontics

 

Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions

date:2013
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Claire Bordes, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure Sensitive Adhesive by Spray-cooling: Optimum Formulation and Processing Conditions.” (May 2013). doi:10.1016/j.apt.2013.05.004.

Advanced Powder Technology

 

Polymer encapsulation of inorganic nanoparticles for biomedical applications

date:2013
références bibliographiques:

Ladj, Rachid, Ahmad Bitar, Mohamed M. Eissa, Hatem Fessi, Yannick Mugnier, Ronan Le Dantec, and Abdelhamid Elaissari. “Polymer Encapsulation of Inorganic Nanoparticles for Biomedical Applications.” 458, no. 1 (December 2013): 230–41. doi:10.1016/j.ijpharm.2013.09.001.
Pages:230-241

International Journal of Pharmaceutics

 

The Development, Physicochemical Characterisation and in Vitro Drug Release Studies of Pectinate Gel Beads Containing Thai Mango Seed Kernel Extract

date:2013
références bibliographiques:

Nithitanakool, Saruth, Pimolpan Pithayanukul, Sandrine Bourgeois, Hatem Fessi, and Rapepol Bavovada. “The Development, Physicochemical Characterisation and in Vitro Drug Release Studies of Pectinate Gel Beads Containing Thai Mango Seed Kernel Extract.” 18, no. 6 (June 3, 2013): 6504–20. doi:10.3390/molecules18066504.
Pages:6504-6520

Molecules

 

Iodinated α-tocopherol nano-emulsions as non-toxic contrast agents for preclinical X-ray imaging

date:2013
références bibliographiques:

Li, Xiang, Nicolas Anton, Guy Zuber, Minjie Zhao, Nadia Messaddeq, François Hallouard, Hatem Fessi, and Thierry F. Vandamme. “Iodinated α-Tocopherol Nano-Emulsions as Non-Toxic Contrast Agents for Preclinical X-Ray Imaging.” 34, no. 2 (January 2013): 481–91. doi:10.1016/j.biomaterials.2012.09.026.
Pages:481-491

Biomaterials

 

Reactive magnetic poly(divinylbenzene-co-glycidyl methacrylate) colloidal particles for specific antigen detection using microcontact printing technique

date:2013
références bibliographiques:

Eissa, Mohamed M., Md. Mahbubor Rahman, Nadia Zine, Nicole Jaffrezic, Abdelhamid Errachid, Hatem Fessi, and Abdelhamid Elaissari. “Reactive Magnetic Poly(divinylbenzene-Co-Glycidyl Methacrylate) Colloidal Particles for Specific Antigen Detection Using Microcontact Printing Technique.” 9, no. 3 (March 2013): 5573–82. doi:10.1016/j.actbio.2012.10.027.
Pages:5573-5582

Acta Biomaterialia

 

Aminodextran-coated potassium niobate (KNbO3) nanocrystals for second harmonic bio-imaging

date:2013
références bibliographiques:

Ladj, Rachid, Thibaud Magouroux, Mohamed Eissa, Marc Dubled, Yannick Mugnier, Ronan Le Dantec, Christine Galez, Jean-Pierre Valour, Hatem Fessi, and Abdelhamid Elaissari. “Aminodextran-Coated Potassium Niobate (KNbO3) Nanocrystals for Second Harmonic Bio-Imaging.” 439 (December 2013): 131–37. doi:10.1016/j.colsurfa.2013.02.025.
Pages:131-137

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Preparation of vitamin E loaded nanocapsules by the nanoprecipitation method: From laboratory scale to large scale using a membrane contactor

date:2012
références bibliographiques:

Khayata, N., W. Abdelwahed, M.F. Chehna, C. Charcosset, and H. Fessi. “Preparation of Vitamin E Loaded Nanocapsules by the Nanoprecipitation Method: From Laboratory Scale to Large Scale Using a Membrane Contactor.” 423, no. 2 (February 2012): 419–27. doi:10.1016/j.ijpharm.2011.12.016.
Pages:419-427

International Journal of Pharmaceutics

 

Preparation, Characterization and Applications of Liposomes: State of the Art

date:2012
références bibliographiques:

Laouini, A., C. Jaafar-Maalej, I. Limayem-Blouza, S. Sfar, C. Charcosset, and H. Fessi. “Preparation, Characterization and Applications of Liposomes: State of the Art.” 1, no. 2 (December 1, 2012): 147–68. doi:10.1166/jcsb.2012.1020.
Pages:147-168

Journal of Colloid Science and Biotechnology

 

Stability study and lyophilization of vitamin E-loaded nanocapsules prepared by membrane contactor

date:2012
références bibliographiques:

Khayata, N., W. Abdelwahed, M.F. Chehna, C. Charcosset, and H. Fessi. “Stability Study and Lyophilization of Vitamin E-Loaded Nanocapsules Prepared by Membrane Contactor.” 439, no. 1–2 (December 2012): 254–59. doi:10.1016/j.ijpharm.2012.09.032.
Pages:254-259

International Journal of Pharmaceutics

 

Electrokinetic properties of poly-ε-caprolactone-based nanoparticles prepared by nanoprecipitation and emulsification-diffusion methods: a comparative study

date:2012
références bibliographiques:

Mora-Huertas, C. E., F. Couenne, H. Fessi, and A. Elaissari. “Electrokinetic Properties of Poly-Ε-Caprolactone-Based Nanoparticles Prepared by Nanoprecipitation and Emulsification-Diffusion Methods: A Comparative Study.” 14, no. 6 (June 4, 2012). doi:10.1007/s11051-012-0876-7.

Journal of Nanoparticle Research

 

Ordonnancement des cuves de décroissance dans un service de médecine nucléaire

date:2012
références bibliographiques:

Hallouard, F., D. Matanza, A. Foucher, H. Fessi, and M. Fraysse. “Ordonnancement Des Cuves de Décroissance Dans Un Service de Médecine Nucléaire.” 47, no. 2 (July 4, 2012): 299–308. doi:10.1051/radiopro/2012014.
Pages:299-308

Radioprotection

 

Pharmacokinetic study of an oral piroxicam formulation containing different molar ratios of β-cyclodextrins

date:2012
références bibliographiques:

Skiba, M., F. Bouchal, T. Boukhris, F. Bounoure, H. Fessi, S. Fatmi, N. Chaffai, and M. Lahiani-Skiba. “Pharmacokinetic Study of an Oral Piroxicam Formulation Containing Different Molar Ratios of Β-Cyclodextrins.” 75, no. 3–4 (June 9, 2012): 311–14. doi:10.1007/s10847-012-0166-0.
Pages:311-314

Journal of Inclusion Phenomena and Macrocyclic Chemistry

 

Electrokinetic properties of poly-ε-caprolactone-based nanoparticles prepared by nanoprecipitation and emulsification-diffusion methods: a comparative study

date:2012
références bibliographiques:

Mora-Huertas, C. E., F. Couenne, H. Fessi, and A. Elaissari. “Electrokinetic Properties of Poly-ε-caprolactone-based Nanoparticles Prepared by Nanoprecipitation and Emulsification-diffusion Methods: a Comparative Study.” 14, no. 6 (June 4, 2012). doi:10.1007/s11051-012-0876-7.

Journal of Nanoparticle Research

 

Argan Oil Nanoemulsions as New Hydrophobic Drug-Loaded Delivery System for Transdermal Application

date:2012
références bibliographiques:

Lococo, D., C. E. Mora-Huertas, H. Fessi, I. Zaanoun, and A. Elaissari. “Argan Oil Nanoemulsions as New Hydrophobic Drug-Loaded Delivery System for Transdermal Application.” 8, no. 5 (October 1, 2012): 843–848. doi:10.1166/jbn.2012.1445.
Pages:843-848

Journal of Biomedical Nanotechnology

 

Nanoparticles via Nanoprecipitation Process

date:2012
références bibliographiques:

Minost, Audrey, Jean Delaveau, Marie-Alexandrine Bolzinger, Hatem Fessi, and Abdelhamid Elaissari. “Nanoparticles via Nanoprecipitation Process.” 6, no. 3 (August 1, 2012): 250–58. doi:10.2174/187221112802652615.
Pages:250-258

Recent Patents on Drug Delivery & Formulation

 

Thermally-Sensitive and Magnetic Poly(N-Vinylcaprolactam)-Based Nanogels by Inverse Miniemulsion Polymerization

date:2012
références bibliographiques:

Medeiros, Simone F., Amilton M. Santos, Hatem Fessi, and Abdelhamid Elaissari. “Thermally-Sensitive and Magnetic Poly(N-Vinylcaprolactam)-Based Nanogels by Inverse Miniemulsion Polymerization.” 1, no. 1 (June 1, 2012): 99–112. doi:10.1166/jcsb.2012.1002.
Pages:99-112

Journal of Colloid Science and Biotechnology

 

Liposome and niosome preparation using a membrane contactor for scale-up

date:2012
références bibliographiques:

Pham, Thi Thuy, Chiraz Jaafar-Maalej, Catherine Charcosset, and Hatem Fessi. “Liposome and Niosome Preparation Using a Membrane Contactor for Scale-Up.” 94 (June 2012): 15–21. doi:10.1016/j.colsurfb.2011.12.036.
Pages:15-21

Colloids and Surfaces B: Biointerfaces

 

Modified double emulsion process as a new route to prepare submicron biodegradable magnetic/polycaprolactone particles for in vivo theranostics

date:2012
références bibliographiques:

Ahmed, Naveed, Millán Michelin-Jamois, Hatem Fessi, and Abdelhamid Elaissari. “Modified Double Emulsion Process as a New Route to Prepare Submicron Biodegradable Magnetic/polycaprolactone Particles for in Vivo Theranostics.” 8, no. 8 (2012): 2554. doi:10.1039/c2sm06872a.
Pages:2554

Soft Matter

 

Engineered Nanoparticulate Drug Delivery Systems: The Next Frontier for Oral Administration?

date:2012
références bibliographiques:

Diab, Roudayna, Chiraz Jaafar-Maalej, Hatem Fessi, and Philippe Maincent. “Engineered Nanoparticulate Drug Delivery Systems: The Next Frontier for Oral Administration?” 14, no. 4 (July 6, 2012): 688–702. doi:10.1208/s12248-012-9377-y.
Pages:688-702

The AAPS Journal

 

Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation

date:2012
références bibliographiques:

Almouazen, Eyad, Sandrine Bourgeois, Lars Petter Jordheim, Hatem Fessi, and Stephanie Briançon. “Nano-Encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation.” , December 8, 2012. doi:10.1007/s11095-012-0949-4.

Pharmaceutical Research

 

Theranostic applications of nanoparticles in cancer

date:2012
références bibliographiques:

Ahmed, Naveed, Hatem Fessi, and Abdelhamid Elaissari. “Theranostic Applications of Nanoparticles in Cancer.” 17, no. 17–18 (September 2012): 928–34. doi:10.1016/j.drudis.2012.03.010.
Pages:928-934

Drug Discovery Today

 

Polymer particle adsorption at textile/liquid interfaces: a simple approach for a new functionalization route

date:2012
références bibliographiques:

Ripoll, Lionel, Claire Bordes, Pedro Marote, Sabrina Etheve, Abdelhamid Elaissari, and Hatem Fessi. “Polymer Particle Adsorption at Textile/liquid Interfaces: A Simple Approach for a New Functionalization Route.” 61, no. 7 (July 2012): 1127–35. doi:10.1002/pi.4190.
Pages:1127-1135

Polymer International

 

Synthesis and Characterization of Thermally and Glucose-Sensitive Poly <I>N</I>-Vinylcaprolactam-Based Microgels

date:2012
références bibliographiques:

Bitar, Ahmad, Hatem Fessi, and Abdelhamid Elaissari. “Synthesis and Characterization of Thermally and Glucose-Sensitive Poly <I>N</I>-Vinylcaprolactam-Based Microgels.” 8, no. 5 (October 1, 2012): 709–719. doi:10.1166/jbn.2012.1439.
Pages:709-719

Journal of Biomedical Nanotechnology

 

Electrokinetic properties of bare or nanoparticle-functionalized textile fabrics

date:2012
références bibliographiques:

Ripoll, Lionel, Claire Bordes, Pedro Marote, Sabrina Etheve, Abdelhamid Elaissari, and Hatem Fessi. “Electrokinetic Properties of Bare or Nanoparticle-Functionalized Textile Fabrics.” 397 (March 2012): 24–32. doi:10.1016/j.colsurfa.2012.01.022.
Pages:24-32

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Encapsulation of a pressure-sensitive adhesive by spray-drying: microparticles preparation and evaluation of their crushing strength

date:2012
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Jean-Pierre Valour, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure-Sensitive Adhesive by Spray-Drying: Microparticles Preparation and Evaluation of Their Crushing Strength.” 29, no. 2 (March 2012): 185–93. doi:10.3109/02652048.2011.642014.
Pages:185-193

Journal of Microencapsulation

 

Membrane emulsification: A promising alternative for vitamin E encapsulation within nano-emulsion

date:2012
références bibliographiques:

Laouini, Abdallah, Hatem Fessi, and Catherine Charcosset. “Membrane Emulsification: A Promising Alternative for Vitamin E Encapsulation within Nano-Emulsion.” 423–24 (December 2012): 85–96. doi:10.1016/j.memsci.2012.07.031.
Pages:85-96

Journal of Membrane Science

 

Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages

date:2012
références bibliographiques:

Almouazen, Eyad, Sandrine Bourgeois, Ali Boussaïd, Pascale Valot, Celine Malleval, Hatem Fessi, Serge Nataf, and Stephanie Briançon. “Development of a Nanoparticle-Based System for the Delivery of Retinoic Acid into Macrophages.” 430, no. 1–2 (July 2012): 207–15. doi:10.1016/j.ijpharm.2012.03.025.
Pages:207-215

International Journal of Pharmaceutics

 

Elaboration of Argan Oil Nanocapsules Containing Naproxen for Cosmetic and Transdermal Local Application

date:2012
références bibliographiques:

Rosset, Valentina, Naveed Ahmed, I. Zaanoun, B. Stella, Hatem Fessi, and Abdelhamid Elaissari. “Elaboration of Argan Oil Nanocapsules Containing Naproxen for Cosmetic and Transdermal Local Application.” 1, no. 2 (December 1, 2012): 218–24. doi:10.1166/jcsb.2012.1023.
Pages:218-224

Journal of Colloid Science and Biotechnology

 

Nanocapsules prepared via nanoprecipitation and emulsification–diffusion methods: Comparative study

date:2012
références bibliographiques:

Mora-Huertas, Claudia Elizabeth, Olivier Garrigues, Hatem Fessi, and Abdelhamid Elaissari. “Nanocapsules Prepared via Nanoprecipitation and Emulsification–diffusion Methods: Comparative Study.” 80, no. 1 (January 2012): 235–39. doi:10.1016/j.ejpb.2011.09.013.
Pages:235-239

European Journal of Pharmaceutics and Biopharmaceutics

 

SHG Active Fe(IO3)3 Particles: From Spherical Nanocrystals to Urchin-Like Microstructures through the Additive-Mediated Microemulsion Route

date:2012
références bibliographiques:

Ladj, Rachid, Moustafa El Kass, Yannick Mugnier, Ronan Le Dantec, Hatem Fessi, Christine Galez, and Abdelhamid Elaissari. “SHG Active Fe(IO3)3 Particles: From Spherical Nanocrystals to Urchin-Like Microstructures through the Additive-Mediated Microemulsion Route.” 12, no. 11 (November 7, 2012): 5387–95. doi:10.1021/cg3009915.
Pages:5387-5395

Crystal Growth & Design

 

Lipid-based carriers: manufacturing and applications for pulmonary route

date:2012
références bibliographiques:

Jaafar-Maalej, Chiraz, Abdelhamid Elaissari, and Hatem Fessi. “Lipid-Based Carriers: Manufacturing and Applications for Pulmonary Route.” 9, no. 9 (September 2012): 1111–27. doi:10.1517/17425247.2012.702751.
Pages:1111-1127

Expert Opinion on Drug Delivery

 

Silica-based nanoparticles for biomedical applications

date:2012
références bibliographiques:

Bitar, Ahmad, Nasir M. Ahmad, Hatem Fessi, and Abdelhamid Elaissari. “Silica-Based Nanoparticles for Biomedical Applications.” 17, no. 19–20 (October 2012): 1147–54. doi:10.1016/j.drudis.2012.06.014.
Pages:1147-1154

Drug Discovery Today

 

Industrial pressure sensitive adhesives suitable for physicochemical microencapsulation

date:2011
références bibliographiques:

Abderrahmen, R., C. Gavory, D. Chaussy, S. Briançon, H. Fessi, and M.N. Belgacem. “Industrial Pressure Sensitive Adhesives Suitable for Physicochemical Microencapsulation.” 31, no. 7 (October 2011): 629–633. doi:10.1016/j.ijadhadh.2011.06.003.
Pages:629-633

International Journal of Adhesion and Adhesives

 

Stimuli-responsive magnetic particles for biomedical applications

date:2011
références bibliographiques:

Medeiros, S.F., A.M. Santos, H. Fessi, and A. Elaissari. “Stimuli-responsive Magnetic Particles for Biomedical Applications.” 403, no. 1–2 (January 2011): 139–161. doi:10.1016/j.ijpharm.2010.10.011.
Pages:139-161

International Journal of Pharmaceutics

 

Liposome preparation using a hollow fiber membrane contactor—Application to spironolactone encapsulation

date:2011
références bibliographiques:

Laouini, A., C. Jaafar-Maalej, S. Sfar, C. Charcosset, and H. Fessi. “Liposome Preparation Using a Hollow Fiber Membrane contactor—Application to Spironolactone Encapsulation.” 415, no. 1–2 (August 2011): 53–61. doi:10.1016/j.ijpharm.2011.05.034.
Pages:53-61

International Journal of Pharmaceutics

 

Influence of process and formulation parameters on the formation of submicron particles by solvent displacement and emulsification–diffusion methods

date:2011
références bibliographiques:

Mora-Huertas, C.E., H. Fessi, and A. Elaissari. “Influence of Process and Formulation Parameters on the Formation of Submicron Particles by Solvent Displacement and Emulsification–diffusion Methods.” 163, no. 2 (April 2011): 90–122. doi:10.1016/j.cis.2011.02.005.
Pages:90-122

Advances in Colloid and Interface Science

 

A new method for liposome preparation using a membrane contactor

date:2011
références bibliographiques:

Jaafar-Maalej, Chiraz, Catherine Charcosset, and Hatem Fessi. “A New Method for Liposome Preparation Using a Membrane Contactor.” 21, no. 3 (September 2011): 213–220. doi:10.3109/08982104.2010.517537.
Pages:213-220

Journal of Liposome Research

 

Process induced transformations during tablet manufacturing: Phase transition analysis of caffeine using DSC and low frequency micro-Raman spectroscopy

date:2011
références bibliographiques:

Hubert, Sébastien, Stéphanie Briancon, Alain Hedoux, Yannick Guinet, Laurent Paccou, Hatem Fessi, and Francois Puel. “Process Induced Transformations during Tablet Manufacturing: Phase Transition Analysis of Caffeine Using DSC and Low Frequency Micro-Raman Spectroscopy.” 420, no. 1 (2011): 76–83. doi:10.1016/j.ijpharm.2011.08.028.
Pages:76-83

International Journal of Pharmaceutics

 

Highly temperature responsive core–shell magnetic particles: Synthesis, characterization and colloidal properties

date:2011
références bibliographiques:

Rahman, Md Mahbubor, Mohamed M. Chehimi, Hatem Fessi, and Abdelhamid Elaissari. “Highly Temperature Responsive Core–shell Magnetic Particles: Synthesis, Characterization and Colloidal Properties.” 360, no. 2 (August 2011): 556–564. doi:10.1016/j.jcis.2011.04.078.
Pages:556-564

Journal of Colloid and Interface Science

 

Study of the Effect of Formulation Parameters/Variables to Control the Nanoencapsulation of Hydrophilic Drug via Double Emulsion Technique

date:2011
références bibliographiques:

Ayoub, Mohamed, Naveed Ahmed, Nader Kalaji, Catherine Charcosset, Ayoub Magdy, Hatem Fessi, and Abdelhamid Elaissari. “Study of the Effect of Formulation Parameters/Variables to Control the Nanoencapsulation of Hydrophilic Drug via Double Emulsion Technique.” 7, no. 2 (April 1, 2011): 255–262. doi:10.1166/jbn.2011.1279.
Pages:255-262

Journal of Biomedical Nanotechnology

 

Beclomethasone-Loaded Lipidic Nanocarriers for Pulmonary Drug Delivery: Preparation, Characterization and <I>In Vitro</I> Drug Release

date:2011
références bibliographiques:

Jaafar-Maalej, Chiraz, Véronique Andrieu, Abdelhamid Elaissari, and Hatem Fessi. “Beclomethasone-Loaded Lipidic Nanocarriers for Pulmonary Drug Delivery: Preparation, Characterization and <I>In Vitro</I> Drug Release.” 11, no. 3 (March 1, 2011): 1841–1851. doi:10.1166/jnn.2011.3119.
Pages:1841-1851

Journal of Nanoscience and Nanotechnology

 

Positive contrast with therapeutic iron nanoparticles at 4.7 T

date:2011
références bibliographiques:

Sigovan, Monica, Misara Hamoudeh, Achraf Al Faraj, Delphine Charpigny, Hatem Fessi, and Emmanuelle Canet-Soulas. “Positive Contrast with Therapeutic Iron Nanoparticles at 4.7 T.” 24, no. 5 (May 24, 2011): 259–265. doi:10.1007/s10334-011-0258-7.
Pages:259-265

Magnetic Resonance Materials in Physics, Biology and Medicine

 

Preparation of Indomethacin-Loaded Lipid Particles by Membrane Emulsification

date:2011
références bibliographiques:

Li, Yang, Hatem Fessi, and Catherine Charcosset. “Preparation of Indomethacin-Loaded Lipid Particles by Membrane Emulsification.” 4, no. 2 (February 1, 2011): 591–595. doi:10.1166/asl.2011.1245.
Pages:591-595

Advanced Science Letters

 

Anisotropic magnetic microparticles from ferrofluid emulsion

date:2011
références bibliographiques:

Rahman, Md Mahbubor, Frank Montagne, Hatem Fessi, and Abdelhamid Elaissari. “Anisotropic Magnetic Microparticles from Ferrofluid Emulsion.” 7, no. 4 (2011): 1483. doi:10.1039/c0sm00602e.
Pages:1483

Soft Matter

 

Effect of cyclodextrins on lonidamine release and in-vitro cytotoxicity

date:2010
références bibliographiques:

Lahiani-Skiba, M., F. Bounoure, H. Fessi, and M. Skiba. “Effect of Cyclodextrins on Lonidamine Release and In-vitro Cytotoxicity.” 69, no. 3–4 (October 1, 2010): 481–485. doi:10.1007/s10847-010-9872-7.
Pages:481-485

Journal of Inclusion Phenomena and Macrocyclic Chemistry

 

rhEGF microsphere formulation and in vitro skin evaluation

date:2010
références bibliographiques:

Haushey, L. Al, M. A. Bolzinger, H. Fessi, and S. Briançon. “rhEGF Microsphere Formulation and in Vitro Skin Evaluation.” 27, no. 1 (January 2010): 14–24. doi:10.3109/02652040902749061.
Pages:14-24

Journal of Microencapsulation

 

Experimental Intracameral Injection of Vancomycin Microparticles in Rabbits

date:2010
références bibliographiques:

Kodjikian, L., J. Couprie, W. Hachicha, Q. Timour, M. Devouassoux, N. Builles, D. Hartmann, and H. Fessi. “Experimental Intracameral Injection of Vancomycin Microparticles in Rabbits.” 51, no. 8 (March 24, 2010): 4125–4132. doi:10.1167/iovs.09-4694.
Pages:4125-4132

Investigative Ophthalmology & Visual Science

 

Polymer-based nanocapsules for drug delivery

date:2010
références bibliographiques:

Mora-Huertas, C.E., H. Fessi, and A. Elaissari. “Polymer-based Nanocapsules for Drug Delivery.” 385, no. 1–2 (January 2010): 113–142. doi:10.1016/j.ijpharm.2009.10.018.
Pages:113-142

International Journal of Pharmaceutics

 

Skin absorption studies of octyl-methoxycinnamate loaded poly(D,L-lactide) nanoparticles: Estimation of the UV filter distribution and release behaviour in skin layers

date:2010
références bibliographiques:

Vettor, M., S. Bourgeois, H. Fessi, J. Pelletier, P. Perugini, F. Pavanetto, and M. A. Bolzinger. “Skin Absorption Studies of Octyl-Methoxycinnamate Loaded poly(D,L-Lactide) Nanoparticles: Estimation of the UV Filter Distribution and Release Behaviour in Skin Layers.” 27, no. 3 (May 2010): 253–62. doi:10.3109/10717540903097770.
Pages:253-262

Journal of Microencapsulation

 

Skin absorption studies of octyl-methoxycinnamate loaded poly(D,L-lactide) nanoparticles: Estimation of the UV filter distribution and release behaviour in skin layers

date:2010
références bibliographiques:

Vettor, M., S. Bourgeois, H. Fessi, J. Pelletier, P. Perugini, F. Pavanetto, and M. A. Bolzinger. “Skin Absorption Studies of Octyl-methoxycinnamate Loaded poly(D,L-lactide) Nanoparticles: Estimation of the UV Filter Distribution and Release Behaviour in Skin Layers.” 27, no. 3 (May 2010): 253–262. doi:10.3109/10717540903097770.
Pages:253-262

Journal of Microencapsulation

 

Synthesis and characterization of novel radiopaque poly(allyl amine) nanoparticles

date:2010
références bibliographiques:

Mawad, Damia, Antonio Lauto, Alexandra Penciu, Henri Méhier, Bernard Fenet, Hatem Fessi, and Yves Chevalier. “Synthesis and Characterization of Novel Radiopaque Poly(allyl Amine) Nanoparticles.” 21, no. 33 (August 20, 2010): 335603. doi:10.1088/0957-4484/21/33/335603.
Pages:335603

Nanotechnology

 

Microencapsulation of cytarabine using poly(ethylene glycol)–poly(ε-caprolactone) diblock copolymers as surfactant agents

date:2010
références bibliographiques:

Diab, Roudayna, Misara Hamoudeh, Olivier Boyron, Abdelhamid Elaissari, and Hatem Fessi. “Microencapsulation of Cytarabine Using Poly(ethylene Glycol)–poly(ε-caprolactone) Diblock Copolymers as Surfactant Agents.” 36, no. 4 (April 2010): 456–469. doi:10.3109/03639040903261989.
Pages:456-469

Drug Development and Industrial Pharmacy

 

Reactive and Highly Submicron Magnetic Latexes for Bionanotechnology Applications

date:2010
références bibliographiques:

Elaissari, Abdelhamid, and Hatem Fessi. “Reactive and Highly Submicron Magnetic Latexes for Bionanotechnology Applications.” 288, no. 1 (February 2010): 115–120. doi:10.1002/masy.201050215.
Pages:115-120

Macromolecular Symposia

 

Controlled Release Carriers of Growth Factors FGF-2 and TGF<I>β</I>1: Synthesis, Characterization and Kinetic Modelling

date:2010
références bibliographiques:

Kalaji, Nader, Alexander Deloge, Nida Sheibat-Othman, Olivier Boyron, Imad About, and Hatem Fessi. “Controlled Release Carriers of Growth Factors FGF-2 and TGF<I>β</I>1: Synthesis, Characterization and Kinetic Modelling.” 6, no. 2 (2010): 106–16. doi:10.1166/jbn.2010.1102.
Pages:106-116

Journal of Biomedical Nanotechnology

 

Ethanol injection method for hydrophilic and lipophilic drug-loaded liposome preparation

date:2010
références bibliographiques:

Jaafar-Maalej, Chiraz, Roudayna Diab, Véronique Andrieu, Abdelhamid Elaissari, and Hatem Fessi. “Ethanol Injection Method for Hydrophilic and Lipophilic Drug-loaded Liposome Preparation.” 20, no. 3 (September 2010): 228–243. doi:10.3109/08982100903347923.
Pages:228-243

Journal of Liposome Research

 

Synthesis of biocompatible and thermally sensitive poly(N-vinylcaprolactam) nanogels via inverse miniemulsion polymerization: Effect of the surfactant concentration

date:2010
références bibliographiques:

Medeiros, Simone F., Amilton M. Santos, Hatem Fessi, and Abdelhamid Elaissari. “Synthesis of Biocompatible and Thermally Sensitive poly(N-vinylcaprolactam) Nanogels via Inverse Miniemulsion Polymerization: Effect of the Surfactant Concentration.” 48, no. 18 (August 5, 2010): 3932–3941. doi:10.1002/pola.24165.
Pages:3932-3941

Journal of Polymer Science Part A: Polymer Chemistry

 

Development of alpha-ocopherol Acetate Nanoparticles: Influence of Preparative Processes

date:2009
références bibliographiques:

Anais, J. P., N. Razzouq, M. Carvalho, C. Fernandez, A. Astier, M. Paul, A. Astier, H. Fessi, and A. M. Lorino. “Development of Alpha-Ocopherol Acetate Nanoparticles: Influence of Preparative Processes.” 35, no. 2 (February 2009): 216–23. doi:10.1080/03639040802248798.
Pages:216-223

Drug Development and Industrial Pharmacy

 

A Novel Preparation of Biodegradable Polymer–Silica Nanocomposites by Two Different Encapsulation Methods

date:2009
références bibliographiques:

Choi, M.-J., S.-G. Min, S. Briancon, and H. Fessi. “A Novel Preparation of Biodegradable Polymer–Silica Nanocomposites by Two Different Encapsulation Methods.” 43, no. 25 (September 3, 2009): 3023–3030. doi:10.1177/0021998309345336.
Pages:3023-3030

Journal of Composite Materials

 

Preparation of solid lipid particles by membrane emulsification—Influence of process parameters

date:2009
références bibliographiques:

D’oria, C., C. Charcosset, A.A. Barresi, and H. Fessi. “Preparation of Solid Lipid Particles by Membrane emulsification—Influence of Process Parameters.” 338, no. 1–3 (April 2009): 114–18. doi:10.1016/j.colsurfa.2009.01.003.
Pages:114-118

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Preparation of solid lipid particles by membrane emulsification—Influence of process parameters

date:2009
références bibliographiques:

D’oria, C., C. Charcosset, A.A. Barresi, and H. Fessi. “Preparation of Solid Lipid Particles by Membrane emulsification—Influence of Process Parameters.” 338, no. 1–3 (April 2009): 114–118. doi:10.1016/j.colsurfa.2009.01.003.
Pages:114-118

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Topical delivery of cosmetics and drugs. Molecular aspects of percutaneous absorption and delivery

Percutaneous penetration/permeation is a useful tool for obtaining qualitative and/or quantitative information on the amount of a drug, a cosmetic substance, or any chemical that may enter a skin compartment or the systemic circulation of the human body for pharmaceutical or cosmetic purposes, or for toxicological studies. In the latter case, the extent entering can then be taken into consideration in order to calculate the margin of safety using the NOAEL (No Observed Adverse Effect Level) of an appropriate repeated dose toxicity study with the respective substance. This paper is a short overview of various aspects of skin penetration/permeation of drugs or cosmetic agents. The literature reports numerous studies on skin structure and skin properties influencing drug/cosmetic agent permeation profiles and kinetic parameters. The extensive research concerning the skin structure for determining the key parameters of the penetration/permeation process is therefore described first. Mathematical models of the skin absorption process for a drug are then discussed. Finally new developments in pharmaceutical and cosmetic fields to enhance drug permeation or to modify the stratum corneum structure are considered.

date:2009
références bibliographiques:

Förster, Matthias, Marie-Alexandrine Bolzinger, Hatem Fessi, and Stephanie Briançon. “Topical Delivery of Cosmetics and Drugs. Molecular Aspects of Percutaneous Absorption and Delivery.” 19, no. 4 (July–August 2009): 309–323. doi:10.1684/ejd.2009.0676.
Pages:309-323

European Journal of Dermatology: EJD

 

Acid–base behavior of a colloidal clays fraction extracted from natural quartz sand: Effect of permanent surface charge

date:2009
références bibliographiques:

Douch, Jamaâ, Mohamed Hamdani, Hatem Fessi, and Abdelhamid Elaissari. “Acid–base Behavior of a Colloidal Clays Fraction Extracted from Natural Quartz Sand: Effect of Permanent Surface Charge.” 338, no. 1–3 (April 2009): 51–60. doi:10.1016/j.colsurfa.2008.12.034.
Pages:51-60

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Colloidal and physicochemical characterization of protein- containing PLGA microspheres before and after drying

date:2009
références bibliographiques:

Kalaji, Nader, Sheibat-Othman, Hassan Saadaoui, Hamid Elaissari, and Hatem Fessi. “Colloidal and Physicochemical Characterization of Protein- Containing PLGA Microspheres before and after Drying.” 10 (2009): 1–12.
Pages:1-12

E-polymer

 

Assessment methods of inhaled aerosols: technical aspects and applications

date:2009
références bibliographiques:

Jaafar-Maalej, Chiraz, Véronique Andrieu, Abdelhamid Elaissari, and Hatem Fessi. “Assessment Methods of Inhaled Aerosols: Technical Aspects and Applications.” 6, no. 9 (September 2009): 941–959. doi:10.1517/17425240903117244.
Pages:941-959

Expert Opinion on Drug Delivery

 

Elaboration of perfect core-shell submicronic magnetic latexes from oil in water ferrofluid droplets for bionanotechnology applications

date:2009
références bibliographiques:

Braconnot, Sébastien, Christine Hoang, Hatem Fessi, and Abdelhamid Elaissari. “Elaboration of Perfect Core-Shell Submicronic Magnetic Latexes from Oil in Water Ferrofluid Droplets for Bionanotechnology Applications.” 29, no. 2 (March 2009): 624–30. doi:10.1016/j.msec.2008.10.039.
Pages:624-630

Materials Science and Engineering: C

 

Preparation, Characterization and <I>In Vitro</I> Evaluation of a New Nucleotide Analogue Prodrug Cyclodextrin Inclusion Complexes

date:2009
références bibliographiques:

Diab, Roudayna, Lars P. Jordheim, Ghania Degobert, Suzanne Peyrottes, Christian Périgaud, Charles Dumontet, and Hatem Fessi. “Preparation, Characterization and <I>In Vitro</I> Evaluation of a New Nucleotide Analogue Prodrug Cyclodextrin Inclusion Complexes.” 9, no. 1 (January 1, 2009): 295–300. doi:10.1166/jnn.2009.J075.
Pages:295-300

Journal of Nanoscience and Nanotechnology

 

Colloidal and physicochemical characterization of proteincontaining poly(lactide-co-glycolide) (PLGA) microspheres before and after drying

AbstractIn the present work, the double emulsion (W/O/W) method was used to microencapsulate a protein model (Bovine Serum Albumin) in a biodegradable polymer poly(lactide-co-glycolide) (50:50) (PLGA). Colloidal and physicochemical characterization of PLGA based microspheres was investigated after their “crude” preparation and after drying and redispersion processes. Particle morphology and size were studied by scanning electron microscopy and by laser diffraction analysis. Electrokinetic study and colloidal stability were also studied as a function of pH and salinity of the medium. Atomic force microscopy (AFM) was used to study the surface properties. It was found that smooth microspheres were obtained after the drying process. The Atomic force microscopy results of microspheres stored for one month in water show softness and surface irregularity caused by the microspheres degradation. The colloidal stability of theses microspheres is mainly governed by repulsive electrostatic interaction due to the PLGA charge. The used amount of stabilizing agent poly(vinyl alcohol) (PVA) is low enough to ensure the sterical stabilization. Drying process has no effect on the surface properties and colloidal stability of the prepared microspheres.

date:2009
références bibliographiques:

Kalaji, Nader, Nida Sheibat-Othman, Hassan Saadaoui, Abdelhamid Elaissari, and Hatem Fessi. “Colloidal and Physicochemical Characterization of Proteincontaining Poly(lactide-Co-Glycolide) (PLGA) Microspheres before and after Drying.” 9, no. 1 (2009): 110–21. http://www.degruyter.com/view/j/epoly.2009.9.issue-1/epoly.2009.9.1.110/epoly.2009.9.1.110.xml?format=INT.
Pages:110-121

e-Polymers

 

Elaboration of radiopaque iodinated nanoparticles for in situ control of local drug delivery

date:2009
références bibliographiques:

Mawad, Damia, Hanna Mouaziz, Alexandra Penciu, Henri Méhier, Bernard Fenet, Hatem Fessi, and Yves Chevalier. “Elaboration of Radiopaque Iodinated Nanoparticles for in Situ Control of Local Drug Delivery.” 30, no. 29 (October 2009): 5667–5674. doi:10.1016/j.biomaterials.2009.06.027.
Pages:5667-5674

Biomaterials

 

Assessment methods of inhaled aerosols: technical aspects and applications

date:2009
références bibliographiques:

Jaafar-Maalej, Chiraz, Véronique Andrieu, Abdelhamid Elaissari, and Hatem Fessi. “Assessment Methods of Inhaled Aerosols: Technical Aspects and Applications.” 6, no. 9 (September 2009): 941–59. doi:10.1517/17425240903117244.
Pages:941-959

Expert Opinion on Drug Delivery

 

Preparation Conditions Effect on the Morphology and Release Kinetics of Biodegradable Particles: A Mathematical Approach

date:2009
références bibliographiques:

Deloge, Alexandre, Nader Kalaji, Nida Sheibat-Othman, Victor Shengzhao Lin, Pierre Farge, and Hatem Fessi. “Preparation Conditions Effect on the Morphology and Release Kinetics of Biodegradable Particles: A Mathematical Approach.” 9, no. 1 (January 1, 2009): 467–74. doi:10.1166/jnn.2009.J067.
Pages:467-474

Journal of Nanoscience and Nanotechnology

 

Inclusion complexes of a nucleotide analogue with hydroxypropyl-beta-cyclodextrin

date:2009
références bibliographiques:

Jordheim, Lars Petter, Ghania Degobert, Roudayna Diab, Suzanne Peyrottes, Christian Périgaud, Charles Dumontet, and Hatem Fessi. “Inclusion Complexes of a Nucleotide Analogue with Hydroxypropyl-Beta-Cyclodextrin.” 63, no. 1–2 (February 2009): 11–16. doi:10.1007/s10847-008-9483-8.
Pages:11-16

Journal of Inclusion Phenomena and Macrocyclic Chemistry