Stéphanie BRIANCON

Professeur– Directrice du LAGEP

  • Génie Pharmacotechnique

Encapsulation nanoparticules – microparticules compression formes solides


Bureau 1 Université Claude Bernard Lyon 1, bât 308G ESCPE-Lyon, 43 bd du 11 Novembre 1918 G222 Villeurbanne 69622 France

Fax bureau 1: 04 72 43 16 99Téléphone bureau 1: 04 72 43 18 93

Model-based optimization of parameters for degradation reaction of an organophosphorus pesticide, paraoxon, using CeO 2 nanoparticles in water media

date:2017
références bibliographiques:

Salerno, Alicia, Isabelle Pitault, Thierry Devers, Jocelyne Pelletier, and Stéphanie Briançon. “Model-Based Optimization of Parameters for Degradation Reaction of an Organophosphorus Pesticide, Paraoxon, Using CeO 2 Nanoparticles in Water Media.” 53 (July 2017): 18–28. https://doi.org/10.1016/j.etap.2017.04.020.
Pages:18-28

Environmental Toxicology and Pharmacology

 

Processing-induced-transformations (PITs) during direct compression: Impact of tablet composition and compression load on phase transition of caffeine

date:2016
références bibliographiques:

Juban, Audrey, Stéphanie Briançon, and François Puel. “Processing-Induced-Transformations (PITs) during Direct Compression: Impact of Tablet Composition and Compression Load on Phase Transition of Caffeine.” 501, no. 1–2 (2016): 253–64. https://doi.org/10.1016/j.ijpharm.2016.01.079.
Pages:253-264

International Journal of Pharmaceutics

 

Pickering emulsions for skin decontamination

date:2016
références bibliographiques:

Salerno, Alicia, Marie-Alexandrine Bolzinger, Pauline Rolland, Yves Chevalier, Denis Josse, and Stéphanie Briançon. “Pickering Emulsions for Skin Decontamination.” 34 (August 2016): 45–54. https://doi.org/10.1016/j.tiv.2016.03.005.
Pages:45-54

Toxicology in Vitro

 

Formulation of orodispersible films for paediatric therapy: investigation of feasibility and stability for tetrabenazine as drug model

date:2016
références bibliographiques:

Senta-Loys, Zoé, Sandrine Bourgeois, Cyril Pailler-Mattei, Géraldine Agusti, Stéphanie Briançon, and Hatem Fessi. “Formulation of Orodispersible Films for Paediatric Therapy: Investigation of Feasibility and Stability for Tetrabenazine as Drug Model.” , September 2016. https://doi.org/10.1111/jphp.12627.

Journal of Pharmacy and Pharmacology

 

Skin Absorption of Anions: Part Two. Skin Absorption of Halide Ions

date:2016
références bibliographiques:

Paweloszek, Raphaël, Stéphanie Briançon, Yves Chevalier, Nicole Gilon-Delepine, Jocelyne Pelletier, and Marie-Alexandrine Bolzinger. “Skin Absorption of Anions: Part Two. Skin Absorption of Halide Ions.” 33, no. 7 (July 2016): 1576–86. https://doi.org/10.1007/s11095-016-1898-0.
Pages:1576-1586

Pharmaceutical Research

 

Processing-induced-transformations (PITs) during direct compression: impact of compression speeds on phase transition of caffeine

date:2016
références bibliographiques:

Juban, Audrey, Stephanie Briancon, and François Puel. “Processing-Induced-Transformations (PITs) during Direct Compression: Impact of Compression Speeds on Phase Transition of Caffeine.” , May 2016, 1–8. https://doi.org/10.1080/03639045.2016.1179753.
Pages:1-8

Drug Development and Industrial Pharmacy

 

Skin Absorption of Anions: Part One. Methodology for In Vitro Cutaneous Absorption Measurements

date:2016
références bibliographiques:

Paweloszek, Raphaël, Stéphanie Briançon, Yves Chevalier, Nicole Gilon-Delepine, Jocelyne Pelletier, and Marie-Alexandrine Bolzinger. “Skin Absorption of Anions: Part One. Methodology for In Vitro Cutaneous Absorption Measurements.” 33, no. 7 (July 2016): 1564–75. https://doi.org/10.1007/s11095-016-1909-1.
Pages:1564-1575

Pharmaceutical Research

 

Influence of main whey protein components on the mechanism of complex coacervation with Acacia gum

date:2015
références bibliographiques:

Ach, Delphine, Stéphanie Briançon, Vincent Dugas, Jocelyne Pelletier, Guy Broze, and Yves Chevalier. “Influence of Main Whey Protein Components on the Mechanism of Complex Coacervation with Acacia Gum.” 481 (September 2015): 367–74. https://doi.org/10.1016/j.colsurfa.2015.06.006.
Pages:367-374

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Hot homogenization process optimization for fragrance encapsulation in solid lipid nanoparticles: Fragrance encapsulation in SLN by hot homogenization process

date:2015
références bibliographiques:

Cortial, Angèle, Marc Vocanson, Estelle Loubry, and Stéphanie Briançon. “Hot Homogenization Process Optimization for Fragrance Encapsulation in Solid Lipid Nanoparticles: Fragrance Encapsulation in SLN by Hot Homogenization Process.” 30, no. 6 (November 2015): 467–77. https://doi.org/10.1002/ffj.3259.
Pages:467-477

Flavour and Fragrance Journal

 

Formation of microcapsules by complex coacervation

date:2015
références bibliographiques:

Ach, Delphine, Stéphanie Briançon, Guy Broze, François Puel, Alain Rivoire, Jean-Marc Galvan, and Yves Chevalier. “Formation of Microcapsules by Complex Coacervation.” 93, no. 2 (February 2015): 183–91. https://doi.org/10.1002/cjce.22086.
Pages:183-191

The Canadian Journal of Chemical Engineering

 

Predictive model for tensile strength of pharmaceutical tablets based on local hardness measurements

date:2015
références bibliographiques:

Juban, Audrey, Cécile Nouguier-Lehon, Stéphanie Briancon, Thierry Hoc, and Francois Puel. “Predictive Model for Tensile Strength of Pharmaceutical Tablets Based on Local Hardness Measurements.” 490, no. 1–2 (July 2015): 438–45. https://doi.org/10.1016/j.ijpharm.2015.05.078.
Pages:438-445

International Journal of Pharmaceutics

 

Encapsulation of hydrophobic allergens into nanoparticles improves the in vitro immunological diagnosis of allergic contact dermatitis

date:2015
références bibliographiques:

Cortial, Angèle, Audrey Nosbaum, Aurore Rozières, Marie Baeck, Laurence de Montjoye, Sophie Grande, Stéphanie Briançon, Jean-François Nicolas, and Marc Vocanson. “Encapsulation of Hydrophobic Allergens into Nanoparticles Improves the in Vitro Immunological Diagnosis of Allergic Contact Dermatitis.” 11, no. 4 (May 2015): 1029–33. https://doi.org/10.1016/j.nano.2015.02.001.
Pages:1029-1033

Nanomedicine: Nanotechnology, Biology and Medicine

 

Skin toxicity of surfactants: Structure/toxicity relationships

date:2015
références bibliographiques:

Lémery, Emmanuelle, Stéphanie Briançon, Yves Chevalier, Claire Bordes, Thierry Oddos, Annie Gohier, and Marie-Alexandrine Bolzinger. “Skin Toxicity of Surfactants: Structure/toxicity Relationships.” 469 (March 2015): 166–79. https://doi.org/10.1016/j.colsurfa.2015.01.019.
Pages:166-179

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions

date:2014
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Claire Bordes, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure Sensitive Adhesive by Spray-Cooling: Optimum Formulation and Processing Conditions.” 25, no. 1 (January 2014): 292–300. https://doi.org/10.1016/j.apt.2013.05.004.
Pages:292-300

Advanced Powder Technology

 

Effectiveness of grafting modes of methoxycinnamate sunscreen onto silica particles

date:2014
références bibliographiques:

Noomane, Ayed, Souhaira Hbaieb, Marie-Alexandrine Bolzinger, Stéphanie Briançon, Yves Chevalier, and Rafik Kalfat. “Effectiveness of Grafting Modes of Methoxycinnamate Sunscreen onto Silica Particles.” 441 (January 2014): 653–63. https://doi.org/10.1016/j.colsurfa.2013.10.029.
Pages:653-663

Colloids and Surfaces A: Physicochemical and Engineering Aspects

 

Hairy skin exposure to VX in vitro: Effectiveness of delayed decontamination

date:2013
références bibliographiques:

Rolland, P., M.-A. Bolzinger, C. Cruz, D. Josse, and S. Briançon. “Hairy Skin Exposure to VX in Vitro: Effectiveness of Delayed Decontamination.” 27, no. 1 (February 2013): 358–66. https://doi.org/10.1016/j.tiv.2012.08.014.
Pages:358-366

Toxicology in Vitro

 

Encapsulation of a pressure sensitive adhesive by spray-cooling: Optimum formulation and processing conditions

date:2013
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Claire Bordes, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure Sensitive Adhesive by Spray-cooling: Optimum Formulation and Processing Conditions.” (May 2013). doi:10.1016/j.apt.2013.05.004.

Advanced Powder Technology

 

Iodinated nano-emulsions as contrast agents for preclinical X-ray imaging: Impact of the free surfactants on the pharmacokinetics

date:2013
références bibliographiques:

Hallouard, François, Stéphanie Briançon, Nicolas Anton, Xiang Li, Thierry Vandamme, and Hatem Fessi. “Iodinated Nano-Emulsions as Contrast Agents for Preclinical X-Ray Imaging: Impact of the Free Surfactants on the Pharmacokinetics.” 83, no. 1 (January 2013): 54–62. https://doi.org/10.1016/j.ejpb.2012.09.003.
Pages:54-62

European Journal of Pharmaceutics and Biopharmaceutics

 

Nano-encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation

date:2012
références bibliographiques:

Almouazen, Eyad, Sandrine Bourgeois, Lars Petter Jordheim, Hatem Fessi, and Stephanie Briançon. “Nano-Encapsulation of Vitamin D3 Active Metabolites for Application in Chemotherapy: Formulation Study and in Vitro Evaluation.” , December 8, 2012. doi:10.1007/s11095-012-0949-4.

Pharmaceutical Research

 

Development of a nanoparticle-based system for the delivery of retinoic acid into macrophages

date:2012
références bibliographiques:

Almouazen, Eyad, Sandrine Bourgeois, Ali Boussaïd, Pascale Valot, Celine Malleval, Hatem Fessi, Serge Nataf, and Stephanie Briançon. “Development of a Nanoparticle-Based System for the Delivery of Retinoic Acid into Macrophages.” 430, no. 1–2 (July 2012): 207–15. https://doi.org/10.1016/j.ijpharm.2012.03.025.
Pages:207-215

International Journal of Pharmaceutics

 

Penetration of drugs through skin, a complex rate-controlling membrane

date:2012
références bibliographiques:

Bolzinger, Marie-Alexandrine, Stéphanie Briançon, Jocelyne Pelletier, and Yves Chevalier. “Penetration of Drugs through Skin, a Complex Rate-Controlling Membrane.” 17, no. 3 (June 2012): 156–65. https://doi.org/10.1016/j.cocis.2012.02.001.
Pages:156-165

Current Opinion in Colloid & Interface Science

 

Encapsulation of a pressure-sensitive adhesive by spray-drying: microparticles preparation and evaluation of their crushing strength

date:2012
références bibliographiques:

Gavory, Cécile, Robin Abderrahmen, Jean-Pierre Valour, Didier Chaussy, Mohamed Naceur Belgacem, Hatem Fessi, and Stéphanie Briançon. “Encapsulation of a Pressure-Sensitive Adhesive by Spray-Drying: Microparticles Preparation and Evaluation of Their Crushing Strength.” 29, no. 2 (March 2012): 185–93. https://doi.org/10.3109/02652048.2011.642014.
Pages:185-193

Journal of Microencapsulation

 

Integrity characterization of myoglobin released from poly(ε-caprolactone) microspheres using two analytical methods: UV/Vis spectrometry and conductometric bi-enzymatic biosensor

date:2011
références bibliographiques:

Hnaien, M., E. Ruffin, C. Bordes, O. Marcillat, F. Lagarde, N. Jaffrezic-renault, and S. Briançon. “Integrity Characterization of Myoglobin Released from Poly(ε-caprolactone) Microspheres Using Two Analytical Methods: UV/Vis Spectrometry and Conductometric Bi-enzymatic Biosensor.” 78, no. 2 (June 2011): 298–305. doi:10.1016/j.ejpb.2011.01.013.
Pages:298-305

European Journal of Pharmaceutics and Biopharmaceutics

 

Human scalp permeability to the chemical warfare agent VX

date:2011
références bibliographiques:

Rolland, P., M.-A. Bolzinger, C. Cruz, S. Briançon, and D. Josse. “Human Scalp Permeability to the Chemical Warfare Agent VX.” 25, no. 8 (December 2011): 1974–1980. doi:10.1016/j.tiv.2011.06.021.
Pages:1974-1980

Toxicology in Vitro

 

Industrial pressure sensitive adhesives suitable for physicochemical microencapsulation

date:2011
références bibliographiques:

Abderrahmen, R., C. Gavory, D. Chaussy, S. Briançon, H. Fessi, and M.N. Belgacem. “Industrial Pressure Sensitive Adhesives Suitable for Physicochemical Microencapsulation.” 31, no. 7 (October 2011): 629–633. doi:10.1016/j.ijadhadh.2011.06.003.
Pages:629-633

International Journal of Adhesion and Adhesives

 

Confocal Raman Microspectroscopy for Evaluating the Stratum Corneum Removal by 3 Standard Methods

date:2011
références bibliographiques:

Förster, M., M.A. Bolzinger, M.R. Rovere, O. Damour, G. Montagnac, and S. Briançon. “Confocal Raman Microspectroscopy for Evaluating the Stratum Corneum Removal by 3 Standard Methods.” 24, no. 2 (2011): 103–112. doi:10.1159/000322306.
Pages:103-112

Skin Pharmacology and Physiology

 

Confocal Raman microspectroscopy of the skin

Confocal Raman spectroscopy is a technique with considerable potential for the non-invasive study of biological tissues and skin samples in vitro or in vivo. It can be used to study skin physiology and possible pathological conditions and to obtain data about molecular composition and the structure of skin, for example, water content, moisturization and changes in the skin barrier function can all be observed. In-depth measurements also allow biopharmaceutical studies, such as analyzing the rate of penetration of a drug and the biochemical changes that may be induced by an applied formulation. Confocal Raman microspectroscopy is now at such a stage of refinement that it opens up new vistas. The big leap forward in its ease of use enables this technology to be used as an analytical method by more and more non-specialist laboratories. This review gives an overview of the state of the art of this technology by presenting an update on the principles of Raman spectroscopy and then by looking at examples of new developments in in vivo and in vitro applications.

date:2011
références bibliographiques:

Förster, Matthias, Marie-Alexandrine Bolzinger, Gilles Montagnac, and Stéphanie Briançon. “Confocal Raman Microspectroscopy of the Skin.” 21, no. 6 (November–December 2011): 851–863. doi:10.1684/ejd.2011.1494.
Pages:851-863

European Journal of Dermatology: EJD

 

Process induced transformations during tablet manufacturing: Phase transition analysis of caffeine using DSC and low frequency micro-Raman spectroscopy

date:2011
références bibliographiques:

Hubert, Sébastien, Stéphanie Briancon, Alain Hedoux, Yannick Guinet, Laurent Paccou, Hatem Fessi, and Francois Puel. “Process Induced Transformations during Tablet Manufacturing: Phase Transition Analysis of Caffeine Using DSC and Low Frequency Micro-Raman Spectroscopy.” 420, no. 1 (2011): 76–83. doi:10.1016/j.ijpharm.2011.08.028.
Pages:76-83

International Journal of Pharmaceutics

 

Ingredients Tracking of Cosmetic Formulations in the Skin: A Confocal Raman Microscopy Investigation

date:2011
références bibliographiques:

Förster, Matthias, Marie-Alexandrine Bolzinger, Delphine Ach, Gilles Montagnac, and Stephanie Briançon. “Ingredients Tracking of Cosmetic Formulations in the Skin: A Confocal Raman Microscopy Investigation.” 28, no. 4 (January 7, 2011): 858–872. doi:10.1007/s11095-010-0342-0.
Pages:858-872

Pharmaceutical Research

 

rhEGF microsphere formulation and in vitro skin evaluation

date:2010
références bibliographiques:

Haushey, L. Al, M. A. Bolzinger, H. Fessi, and S. Briançon. “rhEGF Microsphere Formulation and in Vitro Skin Evaluation.” 27, no. 1 (January 2010): 14–24. doi:10.3109/02652040902749061.
Pages:14-24

Journal of Microencapsulation

 

Skin contamination by radiopharmaceuticals and decontamination strategies

date:2010
références bibliographiques:

Bolzinger, M.A., C. Bolot, G. Galy, A. Chabanel, J. Pelletier, and S. Briançon. “Skin Contamination by Radiopharmaceuticals and Decontamination Strategies.” 402, no. 1–2 (December 15, 2010): 44–49. doi:10.1016/j.ijpharm.2010.09.027.
Pages:44-49

International Journal of Pharmaceutics

 

Monitoring of Protein Release from Poly(<I>ε</I>-caprolactone) Microspheres Using a Conductometric Biosensor

date:2009
références bibliographiques:

Ruffin, E., M. Hnaien, F. Lagarde, C. Bordes, S. Briançon, and N. Jaffrezic Renault. “Monitoring of Protein Release from Poly(<I>ε</I>-caprolactone) Microspheres Using a Conductometric Biosensor.” 7, no. 5 (October 1, 2009): 818–823. doi:10.1166/sl.2009.1155.
Pages:818-823

Sensor Letters

 

A Novel Preparation of Biodegradable Polymer–Silica Nanocomposites by Two Different Encapsulation Methods

date:2009
références bibliographiques:

Choi, M.-J., S.-G. Min, S. Briancon, and H. Fessi. “A Novel Preparation of Biodegradable Polymer–Silica Nanocomposites by Two Different Encapsulation Methods.” 43, no. 25 (September 3, 2009): 3023–3030. doi:10.1177/0021998309345336.
Pages:3023-3030

Journal of Composite Materials

 

Topical delivery of cosmetics and drugs. Molecular aspects of percutaneous absorption and delivery

Percutaneous penetration/permeation is a useful tool for obtaining qualitative and/or quantitative information on the amount of a drug, a cosmetic substance, or any chemical that may enter a skin compartment or the systemic circulation of the human body for pharmaceutical or cosmetic purposes, or for toxicological studies. In the latter case, the extent entering can then be taken into consideration in order to calculate the margin of safety using the NOAEL (No Observed Adverse Effect Level) of an appropriate repeated dose toxicity study with the respective substance. This paper is a short overview of various aspects of skin penetration/permeation of drugs or cosmetic agents. The literature reports numerous studies on skin structure and skin properties influencing drug/cosmetic agent permeation profiles and kinetic parameters. The extensive research concerning the skin structure for determining the key parameters of the penetration/permeation process is therefore described first. Mathematical models of the skin absorption process for a drug are then discussed. Finally new developments in pharmaceutical and cosmetic fields to enhance drug permeation or to modify the stratum corneum structure are considered.

date:2009
références bibliographiques:

Förster, Matthias, Marie-Alexandrine Bolzinger, Hatem Fessi, and Stephanie Briançon. “Topical Delivery of Cosmetics and Drugs. Molecular Aspects of Percutaneous Absorption and Delivery.” 19, no. 4 (July–August 2009): 309–323. doi:10.1684/ejd.2009.0676.
Pages:309-323

European Journal of Dermatology: EJD