Pharmaceutical Engineering (GePharm)

The LAGEP (Laboratoire d’Automatique et de Génie des Procédés) is a research laboratory of the University Lyon 1 and the French national Institute for scientific research (CNRS UMR 5007). It develops pluridisciplinary research in chemical engineering, pharmaceutical engineering and biochemical processes. The LAGEP gathers strong pluridisciplinary competences in close collaboration with national and international research and development centers in industry or in academia.

The “pharmaceutical engineering” group has its strong expertise in drug delivery. This team is mainly working on the formulation of drug delivery systems for topical or parenteral administration and diagnostic applications. The research encompasses several scientific domains and a huge part is devoted to physical chemistry and formulation: development of new drug delivery systems, physical chemistry properties and biological in vitro evaluation. Studies about skin behavior of drug delivery systems devoted to cosmetic or dermopharmaceutic applications are particularly developed, the LAGEP being equipped with high performance tools for in vitro skin assessment.
Three kinds of research works are carried out in the laboratory:
- Physico-chemistry and formulation: search for new drug delivery systems, characterization of their physico-chemical properties and in vitro biopharmaceutical evaluation. Encapsulation of drugs, contrast agents, actives… in polymeric micro/nanoparticles.
- Development of encapsulation processes and drying processes dedicated to particulate systems. Membrane processes are developed due to their ability to form calibrated emulsions and particles with a continuous working. Drying of micro and nanoparticles is essential to guarantee the stability of these systems and their long term storage. Freeze drying and spray drying processes are studied.
- Development of solid dosage forms: tableting, drugs polymorphism, characterization spectroscopic characterization, controlled release.
- Bionanotechnology in vitro. Synthesis of colloidal reactive particles as biomolecules extraction support, as biological tracer, as transport systems…Interaction of biomolecules with these colloids.

Key words : Nanoparticles, microparticles, Pickering emulsions, microemulsions, liposomes, skin permeation, membrane processes, freeze drying, spray drying, spray cooling, tableting, powder, drying, hybrid particles, colloids, in vitro diagnostic, environmental analysis

Director of the Pharmaceutical Engineering, Professeur Hatem Fessi

Yearbook of this department
Last Name First Name Field of expertise Function Email Phone
ALBANO Andrea

Nanomedicine, Gene therapy, mRNA delivery, Autoimmune diseases

Doctorant

04 72 43 18 44
ALLIOD Océane

Contacteur à membrane, Encapsulation

Doctorante

oceane.alliod[A]univ-lyon1.fr 04 72 43 18 81
ALMOUAZEN Eyad

Maitre de conférences

eyad.almouazen[A]univ-lyon1.fr 04 78 77 71 15
ARNAULT Joris

Formulation de mousses extinctrices

Doctorant

joris.arnault[A]univ-lyon1.fr 04 74 70 23 81
ATALLAH Carla Encapsulation, liposomes, antihyperpigmentant.

Doctorante

carla.atallah[A]etu.univ-lyon1.fr 04 72 43 18 65
BADRI Waisudin

Doctorante

04 72 43 18 44
BALEGAMIRE Joelle

Formulation, polymères iodés, fonctionnalisation de nanoparticules, agent de contraste, SPCCT (Spectral Photon Counting CT), radio-opacité

Doctorante

joelle.balegamire[A]univ-lyon1.fr 04 72 43 18 36
BOLZINGER Marie-Alexandrine

Formulation des systèmes dispersés – Pénétration cutanée – Dermopharmacie – Cosmétologie

Professeur marie.bolzinger[A]univ-lyon1.fr 04 72 43 18 33
BORDES Claire Chimiométrie (plans d’expériences, analyse de données), formulation MCU claire.bordes[A]univ-lyon1.fr 04 72 43 18 35
BOURGEOIS Sandrine

Formulation et caractérisation de systèmes micro- et nanoparticulaires – Encapsulation Formulation et caractérisations de formes solides

Maître de Conférences

sandrine.bourgeois[A]univ-lyon1.fr 04 72 43 18 33
BRIANCON Stéphanie

Encapsulation nanoparticules – microparticules compression formes solides

Professeur– Directrice du LAGEP

stephanie.briancon[A]univ-lyon1.fr 04 72 43 18 93
CARTON Flavia

Nano medecine

doctorante carton[A]lagep.univ-lyon1.fr 04 72 43 18 44
CHARCOSSET Catherine

Procédés membranaires, biotechnologies et environement

Directrice de Recherches

catherine.charcosset[A]univ-lyon1.fr 04 72 43 18 34
CHEVALIER Yves

Formulation de nouvelles formes galéniques, Physicochimie des surfaces et des systèmes dispersés, Emulsions, Suspensions, Microémulsions, Tensioactifs, Cyclodextrines

Directeur de Recherches

yves.chevalier[A]univ-lyon1.fr 04 72 43 18 77
DE SENNA CARDOSO Denise

Doctorante

04 72 43 18 36
DUMONT Camille

Nano vecteur lipidique

Doctorante

camille.dumont[A]univ-lyon1.fr 04 72 43 18 94
ELAISSARI Hamid

Directeur de Recherches

abdelhamid.elaissari[A]univ-lyon1.fr 04 72 43 18 41
EPHREM Elissa

Doctorante

elissa.ephrem[A]etu.univ-lyon1.fr 04 72 43 18 81
FESSI Hatem

Nanosphères et Nanocapsules

Professeur

hatem.fessi[A]univ-lyon1.fr 04 72 43 18 64
FESSI Nidhal

Doctorant

nidhal.fessi[A]univ-lyon1.fr 04 72 43 18 36
froiio Francesca

Drug delivery, microencapsulation, antimicrobial, food preservation

doctorante froiio[A]lagep.univ-lyon1.fr
JANIER Marc

Professeur

marc.janier[A]univ-lyon1.fr
KRYZA David

MCU-PH, HDR

david.kryza[A]univ-lyon1.fr 04 78 78 29 06
LALLOZ Augustine

Fabrication et caractérisation de nanoparticules, dermopharmacie

Doctorante

augustine.lalloz[A]univ-lyon1.fr 0478785693
LOLLO Giovanna

Design and development of novel drug delivery nanosystems to overcome physiological barriers for the treatment of various diseases.

Maître de conférences

giovanna.lollo[A]univ-lyon1.fr 04 72 44 85 84
MAGNANO Greta

Nanoparticules de oxyde de cérium, synthèse hydrothermale et synthèse par ablation laser, décontamination cutanée, agents toxiques de la guerre.

Doctorante

greta.magnano[A]univ-lyon1.fr 0478777270
MELICH Romain

Microbulles, Contacteur à membrane, Théranostique

Doctorant

romain.melich[A]univ-lyon1.fr 04 72 43 18 81
NICOLAS Sabrina

Pharmacie galénique / vectorisation / immunothérapie anti-tumorale

Doctorante

sabrina.nicolas[A]univ-lyon1.fr 04 72 43 18 36
RESENDE DE AZEVEDO Jacqueline

Formulation

Maitre de Conferences

jacqueline.resende-de-azevedo[A]univ-lyon1.fr 04 72 43 18 33
ROSSO Annalisa

Oral delivery ; inflammatory bowel diseases; mucus penetration ; nanoemulsion ; hydrogel doped nanoparticles

Doctorantes

annalisa.rosso[A]univ-lyon1.fr 04 72 43 18 44
SIDI-BOUMEDINE Jacqueline Post-Doc sidi-boumedine[A]lagep.univ-lyon1.fr
TARHINI Mohamad

Nanoparticules protéiques et encapsulation

Doctorant

mohamad.tarhini[A]univ-lyon1.fr 04 72 43 18 44
TARNOWSKA Malgorzata

Biopharmaceutical aspects of percutaneous penetration of anionic species

Doctorante

malgorzata.tarnowska[A]univ-lyon1.fr 04 72 43 18 94
TRENQUE Isabelle

Dépollution

Post-doctorante

isabelle.trenque[A]univ-lyon1.fr 04 72 43 18 94
VEGA CHACON Jaime Ricardo

Imagerie bio médicale

Doctorant

04 72 43 18 44